Reduced Susceptibility to Antiseptics Is Conferred by Heterologous Housekeeping Genes
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چکیده
منابع مشابه
Do Housekeeping Genes Exist?
The searching of human housekeeping (HK) genes has been a long quest since the emergence of transcriptomics, and is instrumental for us to understand the structure of genome and the fundamentals of biological processes. The resolved genes are frequently used in evolution studies and as normalization standards in quantitative gene-expression analysis. Within the past 20 years, more than a dozen ...
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Classical Mendelian experiments were conducted to determine the genetics and inheritance of quinclorac and acetolactate synthase (ALS)-inhibitor resistance in a biotype of Galium spurium. Plants were screened with the formulated product of either quinclorac or the ALS-inhibitor, thifensulfuron, at the field dose of 125 or 6 g active ingredient (a.i.) ha respectively. Segregation in the F2 gener...
متن کاملHuman housekeeping genes are compact.
Genome Biol. 2, 1018 13 Gray, M.W. et al. (1999) Mitochondrial evolution. Science 283, 1476–1481 14 Lang, B.F. et al. (1999) A comparative genomics approach to the evolution of eukaryotes and their mitochondria. J. Eukaryot. Microbiol. 46, 320–326 15 Henze, K. and Martin, W. (2001) How do mitochondrial genes get into the nucleus? Trends Genet. 17, 383–387 16 Chinnery, P.F. (2003) Searching for ...
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A dominant gene carried in certain inbred mouse strains confers susceptibility to tumors induced by polyoma virus. This gene, designated Pyvs, was defined in crosses between the highly susceptible C3H/BiDa strain and the highly resistant but H-2k-identical C57BR/cdJ strain. The resistance of C57BR/cdJ mice is overcome by irradiation, indicating an immunological basis. In F1 x C57BR/cdJ backcros...
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Point mutations with unclear molecular mechanisms are often associated with vancomycin resistance in Staphylococcus aureus. Here, we observed that the walK (G223D) mutation caused decreased expression of genes associated with cell wall metabolism, decreased autolytic activity, thickened cell walls, and reduced vancomycin susceptibility. A phosphorylation assay showed that WalK (G223D) exhibited...
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ژورنال
عنوان ژورنال: Microbial Drug Resistance
سال: 2018
ISSN: 1076-6294,1931-8448
DOI: 10.1089/mdr.2017.0105